A botanical initiative for the DSID was established to evaluate levels of ingredients and ingredient constituents in botanical DS. The DSID Working Group identified non-vitamin/mineral bioactive ingredients in DS for analysis and inclusion based on these criteria: public exposure (intake and sales), the availability of validated analytical methods and analytical reference materials, research interest and economic and safety concerns. The top scoring 11 ingredients from this ranking process were: CoQ10, garlic, saw palmetto, ginkgo biloba, glucosamine, ginseng, green tea catechins (EGCG and other catechins), milk thistle, echinacea, flaxseed, and turmeric (curcumin).
Green tea dietary supplements were chosen as the first botanical to be studied because they are commonly consumed and frequently studied for their health benefits. This study (products purchased in 2014-2015) was limited to products containing green tea as the primary ingredient and the only botanical to minimize interferences for comparing results to label claims for green tea and its components.